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Alfredo Nicosia Selected Research

Malaria

1/2020New viral vectors for infectious diseases and cancer.
1/2018Assessment of novel vaccination regimens using viral vectored liver stage malaria vaccines encoding ME-TRAP.
6/2017Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies.
1/2017Safety and Immunogenicity of Malaria Vectored Vaccines Given with Routine Expanded Program on Immunization Vaccines in Gambian Infants and Neonates: A Randomized Controlled Trial.
8/2016Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants.
1/2016Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal.
5/2015Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults.
4/2015Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals.
3/2015Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling.
1/2015Anti-CD81 but not anti-SR-BI blocks Plasmodium falciparum liver infection in a humanized mouse model.
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Alfredo Nicosia Research Topics

Disease

40Infections
11/2021 - 10/2003
24Malaria
01/2020 - 02/2006
23Neoplasms (Cancer)
12/2021 - 01/2008
15Vaccinia
11/2021 - 05/2014
6Persistent Infection
08/2016 - 04/2003
5Chronic Hepatitis C
11/2021 - 02/2012
5Viremia
04/2017 - 02/2006
5Falciparum Malaria (Plasmodium falciparum Malaria)
12/2014 - 12/2011
4Bites and Stings (Sting)
01/2021 - 12/2012
4Reinfection
08/2016 - 11/2014
3Herpes Simplex
01/2021 - 01/2020
3Carcinoma (Carcinomatosis)
01/2018 - 10/2003
3Hepatitis C
05/2016 - 06/2008
3Hepatocellular Carcinoma (Hepatoma)
02/2012 - 10/2002
2Rabies (Hydrophobia)
04/2021 - 01/2020
2Virus Diseases (Viral Diseases)
01/2021 - 05/2016
2Colorectal Neoplasms (Colorectal Cancer)
01/2020 - 01/2018
2Communicable Diseases (Infectious Diseases)
01/2020 - 01/2013
2Disease Progression
09/2019 - 07/2012
2Injection Site Reaction
01/2017 - 08/2015
2Respiratory Tract Infections (Respiratory Tract Infection)
08/2015 - 01/2015
2Liver Diseases (Liver Disease)
11/2014 - 02/2012
1Breast Neoplasms (Breast Cancer)
01/2021
1Smallpox (Variola)
01/2020
1Emerging Communicable Diseases (Emerging Infectious Diseases)
01/2020
1Microsatellite Instability
01/2020
1Melanoma (Melanoma, Malignant)
09/2019
1Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer)
01/2018
1Coinfection
01/2018
1Polyps
01/2018
1Turcot syndrome
01/2018
1Papillomavirus Infections
02/2017
1Ebola Hemorrhagic Fever
01/2017
1Vesicular Stomatitis
04/2016
1Chronic Hepatitis (Chronic Active Hepatitis)
01/2016

Drug/Important Bio-Agent (IBA)

47VaccinesIBA
11/2021 - 02/2006
24AntigensIBA
08/2021 - 02/2009
20Proteins (Proteins, Gene)FDA Link
11/2021 - 04/2003
10Antiviral Agents (Antivirals)IBA
01/2021 - 02/2012
9Monoclonal AntibodiesIBA
01/2015 - 10/2002
8AntibodiesIBA
10/2018 - 08/2007
8EpitopesIBA
01/2018 - 09/2005
6Neutralizing AntibodiesIBA
01/2020 - 05/2014
5Glycoproteins (Glycoprotein)IBA
01/2020 - 10/2002
5ThrombospondinsIBA
01/2018 - 01/2013
4Peptides (Polypeptides)IBA
08/2021 - 01/2012
4Biological ProductsIBA
01/2021 - 01/2008
4Immune Checkpoint InhibitorsIBA
11/2020 - 01/2017
4Scavenger Receptors (Scavenger Receptor)IBA
11/2014 - 10/2003
3RNA (Ribonucleic Acid)IBA
11/2021 - 07/2005
3Neoplasm Antigens (Tumor Antigens)IBA
01/2021 - 01/2019
3InterferonsIBA
01/2021 - 11/2014
3Malaria VaccinesIBA
01/2016 - 12/2012
2Pharmaceutical PreparationsIBA
11/2021 - 01/2015
2Interleukin-12 (IL 12)IBA
12/2020 - 01/2018
2DNA (Deoxyribonucleic Acid)IBA
11/2020 - 01/2020
2Messenger RNA (mRNA)IBA
01/2020 - 04/2010
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2018 - 10/2012
2Rabies Vaccines (Rabies Vaccine)FDA Link
01/2016 - 05/2015
2Tight Junction ProteinsIBA
01/2016 - 01/2015
2Antimalarials (Antimalarial Agents)IBA
01/2016 - 05/2015
2Claudin-1IBA
01/2016 - 01/2015
21- acetyl- 1,2,3,3a,8,8a- hexahydro- 8a- hydroxy- 5- methoxypyrrolo(2,3- b)indole (CHMI)IBA
04/2015 - 01/2013
2Recombinant ProteinsIBA
12/2014 - 01/2012
2Adenovirus VaccinesIBA
05/2014 - 05/2014
2Subunit VaccinesIBA
01/2013 - 12/2010
2Merozoite Surface Protein 1 (MSA1)IBA
12/2012 - 12/2011
2Lipoproteins (Lipoprotein)IBA
01/2010 - 08/2007
2HDL LipoproteinsIBA
08/2007 - 10/2003
1Adenosine Triphosphate (ATP)IBA
12/2021
1Purinergic P1 Receptors (Adenosine Receptor)IBA
12/2021
1Adenosine DeaminaseIBA
12/2021
1Adenosine (Adenocard)FDA LinkGeneric
12/2021
1Drug CombinationsIBA
11/2021
1bempegaldesleukinIBA
11/2021
1Immunoconjugates (Immunoconjugate)IBA
01/2021
1Complement System Proteins (Complement)IBA
01/2021
1MesothelinIBA
01/2021
1NectinsIBA
01/2021
1CytokinesIBA
12/2020
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
12/2020
1Interferon Type IIBA
11/2020
1cyclic guanosine monophosphate-adenosine monophosphateIBA
11/2020
1IpilimumabIBA
08/2020
1LigandsIBA
08/2020
1Cancer VaccinesIBA
01/2020
1SolutionsIBA
01/2020
1SurvivinIBA
01/2020
1atezolizumabIBA
11/2019
1Caspase 3 (Caspase-3)IBA
11/2019
1Illicit Drugs (Recreational Drugs)IBA
01/2018
1B7-H1 AntigenIBA
01/2018
1Papillomavirus Vaccines (HPV Vaccines)IBA
02/2017
1Artificial ReceptorsIBA
01/2017
1human ERBB2 proteinIBA
01/2017
1Viral ProteinsIBA
12/2016

Therapy/Procedure

9Therapeutics
11/2021 - 02/2012
4Immunotherapy
12/2021 - 02/2006
4Liver Transplantation
01/2015 - 02/2012
1Radiotherapy
09/2019